Product Name :
25-O-Deacetyl Rifabutin (CAS 100324-63-8)
Synonym :
25-Hydroxy Rifabutin; 25-O-Deacetylrifabutin; 25-O-Desacetylrifabutin
Application :
25-O-Deacetyl Rifabutin is a metabolite of Rifabutin which exhibits antibacterial properties.
CAS:
100324-63-8
Purity:
Molecular Weight:
804.97
Formula :
C44H60N4O10
Physical state:
Solid
solubility :
Soluble in Chloroform and Methanol
Shipping Condition :
Store at -20° C
Melting point:
150-160° C
SMILES:
C[C@H]1/C=C/C=C(/C(=O)NC2=C3C(=NC4(N3)CCN(CC4)C(C)(C)C)C5=C6C(=C(C(=C5C2=O)O)C)O[C@@](C6=O)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)O)C)OC)C)\\C
References:
:Absorption, disposition, and urinary metabolism of 14C-rifabutin in rats.Ethyl 4-methyl-1H-pyrrole-2-carboxylate manufacturer | Battaglia, R.2,5-Dimethoxyterephthalaldehyde structure , et al.PMID:33705323 1991. Antimicrob Agents Chemother. 35: 1391-6. PMID: 1656861In vivo disposition and metabolism by liver and enterocyte microsomes of the antitubercular drug rifabutin in rats. | Koudriakova, T., et al. 1996. J Pharmacol Exp Ther. 279: 1300-9. PMID: 8968354A model based assessment of redistribution dependent elimination and bioavailability of rifabutin. | Li, RC., et al. 1996. Biopharm Drug Dispos. 17: 223-36. PMID: 8983397