Product Name :
p38 Recombinant Rabbit Monoclonal Antibody [JF55-07]
Predicted band size :
41 kDa
Observed band size :
38 kDa
Synonyms:
CSAID-binding protein antibody Csaids binding protein antibody CSBP antibody CSBP1 antibody CSBP2 antibody CSPB1 antibody Cytokine suppressive anti-inflammatory drug-binding protein antibody EXIP antibody MAP kinase 14 antibody MAP kinase MXI2 antibody 展开
Function :
MAP (mitogen-activated protein) kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. p38α, p38β and p38γ, also known as MAPK14, MAPK11 and MAPK12, respectively, each contain one protein kinase domain and belong to the MAP kinase family. Expressed in different areas throughout the body with common expression patterns in heart, p38 proteins use magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins. Via their catalytic activity, p38α, p38β and p38γ are involved in a variety of events throughout the cell, including signal transduction pathways, cytokine production and cell proliferation and differentiation. The p38 proteins are subject to phosphoryation on Thr and Tyr residues, an event which is thought to activate the phosphorylated protein.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within C-terminal human MAPK14.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IF-Tissue, IHC-P, FC
Coupling :
unconjugated
Clone number:
JF55-07
RRID:
AB_3073466
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.(Diacetoxyiodo)benzene Chemical name Aliquot store at -20℃ or -80℃.2-Fluoroacrylic acid Chemical name Avoid repeated freeze / thaw cycles.PMID:33645897
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 41 kDa
Positive control :
HeLa cell lysate, Jurkat cell lysate, HEK-293 cell lysate, NIH/3T3 cell lysate, Neuro-2a cell lysate, RAW264.7 cell lysate, PC-12 cell lysate, C6 cell lysate, THP-1 cell lysate, C2C12 cell lysate, rat kidney tissue lysate, mouse kidney tissue lysate, RAW264.7, PC-12, Hela, 293T, mouse heart tissue.