Product Name :
p15 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
CDK inhibitory protein antibody CDK4B Inhibitor antibody Cdkn2b antibody CDN2B_HUMAN antibody Cyclin dependent kinase 4 inhibitor B antibody Cyclin Dependent Kinase Inhibitor 2B antibody Cyclin dependent kinase inhibitor 2B p15 inhibits CDK4 antibody Cyclin dependent kinases 4 and 6 binding protein antibody Cyclin-dependent kinase 4 inhibitor B antibody INK4B antibody 展开
Function :
This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression.1380500-86-6 Chemscene The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition.6-Bromo-2-fluoro-3-nitropyridine web Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.PMID:33420637
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
The antiserum was produced against synthesized peptide derived from human p15 INK. AA range:89-138
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P, IF
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
14 kDa
Positive control :
Heart,Skin,