Product Name :
P63 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
AIS antibody Amplified in squamous cell carcinoma antibody B(p51A) antibody B(p51B) antibody Chronic ulcerative stomatitis protein antibody CUSP antibody DN p63 alpha 1 antibody DNp63 antibody EEC3 antibody id:ibd3516 antibody 展开
Function :
Tumor protein p63 is a member of the p53 family of transcription factors. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. TP63 mutations underlie several malformation syndromes that include cleft lip and/or palate as a hallmark feature. p63 immunostaining has utility for head and neck squamous cell carcinomas, differentiating prostatic adenocarcinoma (the most common type of prostate cancer) and benign prostatic tissue; normal prostatic glands stain with p63 (as they have basal cells), while the malignant glands in prostatic adenocarcinoma (which lacks these cells) do not. P63 is also helpful in distinguishing poorly differentiated squamous cell carcinoma from small cell carcinoma or adenocarcinoma.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within human P63 aa 152-196.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
RRID:
AB_3073258
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃.Formula of (3-Bromo-1-propyn-1-yl)cyclopropane Avoid repeated freeze / thaw cycles.Formula of Triazabicyclodecene
Storage buffer solution:
1*PBS (pH7.PMID:33683447 4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 77 kDa
Positive control :
MCF-7, human lung cancer tissue, Hela